Josh,
Enfocus, Dynagram, Tools4Media and Alwan are holding a Webinar on December 4th showing the basics of this sort of workflow.
Here's the link to the Press Release:
Enfocus to offer Automation and Web-to-print Webinar Series - Printing Industry News from WhatTheyThink
And here's the link to sign up:
https://www1.gotomeeting.com/register/419941049
You should probably join into this webinar... you'd have direct access to experts from these companies and maybe you'd get some good idea's. We'll be showing our inpO2 Imposition product with Switch for automated prepress and web to print workflows doing just the sort of work you're looking at solving.
Come on and join in!
Michael Reiher
Director of Sales and Marketing
Dynagram