What I am questioning is if Mac OS 10.9 or the Epson driver for the 7880 could be causing a problem with providing occur.
Yes. They absolutely can.
In fact, my guess from what you've described is that's most likely your problem.
For several years now, the old tried and true Mac/Photoshop/Epson setup that most serious photographers used for so long has been so suspect that most people have abandoned it.
I've read a bunch about the why's of this over the years, but the only parts that really stick are that Apple is huge and arrogant now, and assumes that no one can know more than them, so they won't admit there's even an issue, which at its core has something to do with how their printer architecture changed from something to something a few versions of OS ago.
What you have to have is no input from Colorsync to the printer, and sometimes that can be pretty problematic to determine. Some versions of some drivers for some Epsons can show Colorsync and vendor grayed out and still work. Others not. Sometimes you can have a workflow that works, do an upgrade, and it will change.
One reason to use a RIP is that a RIP can eliminate the OS from the printing equation. However, these days, there are more than a few inexpensive "RIP's" available for Mac that do not.
If you're making a profile, I'd assume you have Photoshop or some color aware software with which you're going to use it.
And, i1 Profiler will run on either platform, Windows or Mac.
So if I was in your shoes, I'd use ACPU to print some patches, make a profile, and then test print with the profile, all in Windows.
If you're happy with the result, install the profile on your Mac, and with all printer settings the same, test it again. The test prints should match. If they don't, the Mac is likely the culprit.
Oh, and also if I was in your shoes, I'd take the iO table, sell it on eBay, and use the money to hire a color consultant to show you how to do this right (and and maybe not waste money in the future on things like an iO table.) You can read your patches by hand, and you'll get a much truer result; the iO table is a very inconsistent device.
(Edited to add: Fiery XF is a full-bore, top-of-the line RIP. Properly installed and profiled, yes, it will solve any OS related issues, as it will take the OS out of the printing equation.)
Mike Adams
Correct Color