I'm not extremely well-versed in memory, but 1333 MHz is a very slow clock speed compared to modern memory sticks, and DDR3 is not modern in the computational world, so you might be suffering problems due to inefficient use of your memory due to those two things. I have 16 GB of DDR4 @ 3200 MHz in my system currently, and never have any multitasking issues. It could also just be the fact that you are using a Mac. Only a guess in that department, as I don't have any empirical data to show similar workloads between our iMac 5k and my machine, which have almost the same specifications.