It is hard to say what the make ready time is for your enviroment. For color critical work it takes about 2 minutes to calibrate the machine for a substrate. It takes about 3 -5 minutes make an output profile for a specific substrate. If you have to do other adjustments like density uniformity adjustment and front to back registration that takes another 5 minutes.
So with those routines the machine will be occupied for about 15 minutes. That is the time for the machine to be occupied, operator can do something else during the time the machine is doing adjustments.
Before press print you have to do some selections, f.ex. which paper, from which tray, what profiles it uses and what kind of finishing you want to use. Ofcourse all this can be also automated via hotfolders or presets.